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Difference between revisions of "Pancreas"
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→Pancreatic ectopia: +Pancreatic NETs
(→Ductal adenocarcinoma: rename more formal name) |
(→Pancreatic ectopia: +Pancreatic NETs) |
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==Pancreatic ectopia== | ==Pancreatic ectopia== | ||
===General=== | |||
*May be confused with something pathologic. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Consists of pancreatic acini ''and'' pancreatic ducts. | *Consists of pancreatic acini ''and'' pancreatic ducts. | ||
*+/-Islets of Langerhans. | *+/-Islets of Langerhans. | ||
==Pancreatic neuroendocrine tumour== | |||
{{Main|Neuroendocrine tumour}} | |||
*Abbreviated ''PanNET''.<ref name=pmid22198808/> | |||
*[[AKA]] ''pancreatic islet cell tumour''.<ref name=pmid22198808>{{Cite journal | last1 = Burns | first1 = WR. | last2 = Edil | first2 = BH. | title = Neuroendocrine Pancreatic Tumors: Guidelines for Management and Update. | journal = Curr Treat Options Oncol | volume = | issue = | pages = | month = Dec | year = 2011 | doi = 10.1007/s11864-011-0172-2 | PMID = 22198808 }}</ref> | |||
*[[AKA]] ''islet cell tumour''. | |||
===General=== | |||
*Rare. | |||
*Presentation depends on subtype, e.g. for ''insulinoma'' the typical presentation is hypoglycemia. | |||
====Classification==== | |||
Based on peptide produced: | |||
#Glucagon from alpha cells (glucagonoma). | |||
#Insulin from beta cells (insulinoma) - most common ~ 50% of islet cell tumours. | |||
#Somatostatin from D cells (somatostatinoma). | |||
#Pancreatic polypeptide from PP cells. | |||
===Microscopic=== | |||
Features: | |||
*Nests of cells. | |||
*Stippled chromatin. | |||
Images: | |||
*[http://path.upmc.edu/cases/case172/micro.html Islet cell tumour (upmc.edu)]. | |||
==See also== | ==See also== | ||