Difference between revisions of "Gastrointestinal tract polyps"

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(→‎Peutz-Jeghers polyp: more clinical)
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===Traditional adenoma===
===Traditional adenoma===
====Microscopic====
====Microscopic====
*Nuclear changes at the surface (of the mucosa) - '''key feature'''.
#Nuclear changes at the surface (of the mucosa) - '''key feature'''.
**Loss of nuclear polarity (nuclei no longer on basement membrane).
#*Cigar-shaped (elongated) nucleus (usu. length:width > 3:1) - '''key feature'''.
**Nuclear crowding/pseudostratification (key feature).
#**Normal nuclei are round.
**Hyperchromasia (more blue).
#*Nuclear crowding/pseudostratification - '''key feature'''.
**Cigar-shaped (elongated) nucleus - length:width > 3:1 (key feature).
#*Nuclear hyperchromasia (more blue).
***Normal nuclei are round.
#*+/-Loss of nuclear polarity (nuclei no longer on basement membrane).
*Loss/decrease of goblet cells.
#Loss/decrease of goblet cells (common).
*Cytoplasmic hyperchromasia.
#Cytoplasmic hyperchromasia.


Notes:
Notes:
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