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Difference between revisions of "Spleen"
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→Weird stuff: +HSTL
(→Splenic enlargement: more) |
(→Weird stuff: +HSTL) |
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*Muscle-specific actin +ve/-ve. | *Muscle-specific actin +ve/-ve. | ||
*EMA +ve/-ve. | *EMA +ve/-ve. | ||
==Hepatosplenic T-cell lymphoma== | |||
*[[AKA]] ''hepatosplenic γδ T-cell lymphoma''. | |||
*Abbreviated ''HSTL''. | |||
===General=== | |||
*Rare. | |||
Clinical triad: | |||
#Hepatosplenomegaly. | |||
#Cytopenias ([[anemia]], thrombocytopenia). | |||
#Sinusoidal tropism. | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP595>{{Ref WMSP|595}}</ref> | |||
*Small cell lymphoma. | |||
DDx: | |||
*[[Hairy cell leukemia]]. | |||
===IHC=== | |||
Features:<ref name=Ref_WMSP595>{{Ref WMSP|595}}</ref> | |||
*CD4 -ve. | |||
*CD8 -ve. | |||
=See also= | =See also= | ||