Central neurocytoma
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Central neurocytoma, abbreviated CNC, is a rare neuropathology tumour.
General
Gross/radiology
Microscopic
Features:[4]
- Perivascular pseudorosette = circular/flower-like arrangement of cells with blood vessel at the centre.[5]
- Islands of neuropil.
- Polygonal cells with a perinuclear halo.
DDx:
DDx of perivascular pseudorosette:
- Ependymoma.
- Medulloblastoma, PNET.
- Glioblastomas.
Images
Central neurocytoma - intermed. mag. (WC)
Central neurocytoma - oligodendrogllioma-like area - high mag. (WC)
Central neurocytoma - pseudorosettes - high mag. (WC)
Central neurocytoma - pseudorossettes - very high mag. (WC)
www:
IHC
- MIB1 - high may predict re-occurance.[6]
See also
References
- ↑ 1.0 1.1 Chuang, MT.; Lin, WC.; Tsai, HY.; Liu, GC.; Hu, SW.; Chiang, IC.. "3-T proton magnetic resonance spectroscopy of central neurocytoma: 3 case reports and review of the literature.". J Comput Assist Tomogr 29 (5): 683-8. PMID 16163043.
- ↑ URL: http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm. Accessed on: 12 January 2012.
- ↑ Kerkeni, A.; Ben Lakhdher, Z.; Rkhami, M.; Sebai, R.; Belguith, L.; Khaldi, M.; Ben Hamouda, M. (Oct 2010). "[Central neurocytoma: Study of 32 cases and review of the literature].". Neurochirurgie 56 (5): 408-14. doi:10.1016/j.neuchi.2010.07.001. PMID 20692674.
- ↑ URL: http://moon.ouhsc.edu/kfung/jty1/Com/Com307-1-Diss.htm. Accessed on: 27 May 2011.
- ↑ Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
- ↑ Schmidt, MH.; Gottfried, ON.; von Koch, CS.; Chang, SM.; McDermott, MW. (Feb 2004). "Central neurocytoma: a review.". J Neurooncol 66 (3): 377-84. PMID 15015671.