Splendore-Hoeppli phenomenon

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The Splendore-Hoeppli phenomenon is the presence of deeply eosinophilic material, typically surrounding micro-organisms.[1] It it thought to be composed of immunoglobulin and necrotic debris rich in microbial antigen.

Suppurative lymphadenitis in the neck caused by Actinomyces infection. The eosinophilc rim represents the Splendore-Hoeppli phenomenon.

References

  1. ↑ Gopinath D (2018). "Splendore-Hoeppli phenomenon". J Oral Maxillofac Pathol 22 (2): 161–162. doi:10.4103/jomfp.JOMFP_79_18. PMC 6097361. PMID 30158765. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097361/.

See also

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