Foregut primary carcinomas

Foregut primary carcinomas can be difficult to definitively categorize on the basis of pathology alone, as their immunostaining patterns significantly overlap.

Foregut primary directs to this article.

Foregut

The foregut includes the following:

• Esophagus.
• Stomach.
• Duodenum, proximal portion - to the ampulla of Vater.
• Liver.
• Gallbladder.
• Pancreas.
• Lower respiratory tract.

IHC

Foregut carcinomas are typically:

• CK7 +ve.
• CK20 -ve.
• CDX2 -ve.

A foregut primary panel for liver lesions:

• AE1/AE3, CK7, CK20, CK19, CDX2, CA-125, HepPar-1, GATA3, TTF-1.

See also

• Gastrointestinal pathology.