TDP-43
TAR-DNA-binding Protein 43, abbreviated TDP-43 is a neuropathology immunostain used in neurodegenerative diseases.
- Nuclear staining.
| TDP-43 | |
|---|---|
| Immunostain in short | |
 TDP-43 staining in FTLD-TDP43. (WC) | |
| Normal staining pattern | nuclear staining (physiological) |
| Positive | cytoplasmatic staining (pathological) |
Inclusion morphology
- fine / coarse skeins.
- dot-like.
- dense-round inclusions.
Inclusions found
- FTLD TDP-43
- Alzheimer disease.[1]