Cribriform pattern

Cribriform pattern is a morphologic pattern that is common in pathology, and may be seen in benign and malignant tissue.

Cribriform pattern (ADH). H&E stain. (WC/Nephron)

Cribriform pattern (cribriform adenocarcinoma of the tongue). H&E stain. (WC/Nephron)

Definition

Pierced with small holes.

Some considerations

Breast:

• Atypical ductal hyperplasia.
• Cribriform DCIS.

Prostate:

• Cribriform high grade prostatic intraepithelial neoplasia.

Gastrointestinal tract:

• Cribriforming in a tubular adenoma with high-grade dysplasia.

Gynecology:

• Endometrioid endometrial carcinoma.

See also

• Morphologic patterns.
• Adenocarcinoma.