Glomangiopericytoma

Glomangiopericytoma, also known as sinonasal-type hemangiopericytoma and sinonasal hemangiopericytoma,

Sinonasal hemangiopericytoma may be abbreviated SNHPC.

General

• May be associated with oncogenic osteomalacia.
• Thought to arise from the pericytes.
• Rare <1% of sinonasal tumours.

Microscopic

Features:

• Ahort spindle cells/epithelioid cells with:
  • Bland round/oval nuclei with fine chromatin.
  • Scant cytoplasm.

Note:

• Superficial submucosal tissue spared.

DDx:

• Phosphaturic mesenchymal tumour, mixed connective tissue type - grungy calcs, acellular matrix deposition.
• Other small round cell tumours.

Images

• SNHPC - low mag. (nih.gov).
• SNHPC - high mag. (nih.gov).
• SNHPC (nih.gov).

IHC

Features:

• Vimentin +ve.
• SMA +ve.
• MSA +ve.
• CD31 -ve.
• CD34 -ve.

See also

• Hemangiopericytoma.