Squamous cell carcinoma of the penis
Jump to navigation
Jump to search
Squamous cell carcinoma of the penis is the most common malignancy of the penis.
Squamous cell carcinoma of the penis | |
---|---|
Diagnosis in short | |
Squamous carcinoma of the penis. H&E stain. | |
LM DDx | squamous dysplasia, pseudoepitheliomatous hyperplasia |
Gross | mass lesion, scaly patches/nodules, usu. erythematous, +/-ulceration. |
Site | penis |
| |
Clinical history | uncircumcised |
Prevalence | uncommon overall, most common form of penis cancer |
Prognosis | good |
Treatment | surgery |
General
- Not very common overall.[1]
- Most common form of penis cancer.
- Non-squamous penis cancer only ~5% of cases.[2]
Epidemiology:[1]
- Median age ~ 67 years old.
- Usually a good outcome - 5 year cause specific survival ~ 81%.[1]
Gross
- Scaly patches/nodules.
- Usu. erythematous.
- +/-Ulceration.
Microscopic
Features:
Notes:
- Usually grade 2.[1]
- Lymphovascular invasion - prognostically important,[3] and changes the T-stage for pT1a tumours to pT1b.
DDx:
- Squamous dysplasia.
- Pseudoepitheliomatous hyperplasia.
Staging
T-stage:
- pT1a - subepithelial tissue involved, no LVI, not poorly differentiated (G3 or G4).
- pT1b - subepithelial tissue involved with LVI or poorly differentiated.
- pT2 - corpus spongiosum or cavernosum involved.
- pT3 - urethral involvement.
- pT4 - adjacent structure(s) involved.
Images
Sign out
TIP OF PENIS, PARTIAL PENECTOMY: - INVASIVE SQUAMOUS CELL CARCINOMA, MODERATELY DIFFERENTIATED. -- SURGICAL MARGINS NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY. -- PLEASE SEE TUMOUR SUMMARY.
TIP OF PENIS, PARTIAL PENECTOMY: - INVASIVE SQUAMOUS CELL CARCINOMA OF CORONAL SULCUS, MODERATELY DIFFERENTIATED. -- SURGICAL MARGINS NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY. - LICHEN SCLEROSIS. - POST-SURGICAL CHANGES (GRANULOMATOUS INFLAMMATION (NON-NECROTIZING), SIDEROPHAGES). COMMENT: This lesion was previously excised. The surgical clearance is 1 mm. The tumour thickness is approximately 4 mm. No lymphovascular invasion is identified. No lymphovascular invasion is identified. No corpus spongiosum or corpus cavernosum invasion is seen. The staging is unchanged.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Burt, LM.; Shrieve, DC.; Tward, JD. (Jan 2014). "Stage presentation, care patterns, and treatment outcomes for squamous cell carcinoma of the penis.". Int J Radiat Oncol Biol Phys 88 (1): 94-100. doi:10.1016/j.ijrobp.2013.08.013. PMID 24119832.
- ↑ Moses, KA.; Sfakianos, JP.; Winer, A.; Bernstein, M.; Russo, P.; Dalbagni, G. (Dec 2013). "Non-squamous cell carcinoma of the penis: single-center, 15-year experience.". World J Urol. doi:10.1007/s00345-013-1216-y. PMID 24292119.
- ↑ Bhagat, SK.; Gopalakrishnan, G.; Kekre, NS.; Chacko, NK.; Kumar, S.; Manipadam, MT.; Samuel, P. (Feb 2010). "Factors predicting inguinal node metastasis in squamous cell cancer of penis.". World J Urol 28 (1): 93-8. doi:10.1007/s00345-009-0421-1. PMID 19488760.