Pseudoepitheliomatous hyperplasia
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Pseudoepitheliomatous hyperplasia, abbreviated PEH, is a benign reactive change of squamous mucosa that can mimic squamous cell carcinoma.
General
- Benign.
- Not common.
It is seen in:
- Fungal infections.
- Inflammatory papillary hyperplasia.
- Granular cell tumour.
- Adjacent to an ulcer.
- May form after an injury to the skin.[1]
Microscopic
Features:[2]
- Acanthosis (epidermal thickening) - irregular .[3]
- Involves both follicles and and non-follicular epidermis.
- Hyperkeratosis - thickening of the stratum corneum.
- Parakeratosis - nuclei in the stratum corneum.
DDx:
Images
References
- ↑ Fu, X.; Jiang, D.; Chen, W.; Sun Bs, T.; Sheng, Z.. "Pseudoepitheliomatous hyperplasia formation after skin injury.". Wound Repair Regen 15 (1): 39-46. doi:10.1111/j.1524-475X.2006.00183.x. PMID 17244318.
- ↑ Cui, W.; McGregor, DH.; Stark, SP.; Ulusarac, O.; Mathur, SC. (Jul 2007). "Pseudoepitheliomatous hyperplasia - an unusual reaction following tattoo: report of a case and review of the literature.". Int J Dermatol 46 (7): 743-5. doi:10.1111/j.1365-4632.2007.03150.x. PMID 17614808.
- ↑ Zayour, M.; Lazova, R. (Apr 2011). "Pseudoepitheliomatous hyperplasia: a review.". Am J Dermatopathol 33 (2): 112-22; quiz 123-6. doi:10.1097/DAD.0b013e3181fcfb47. PMID 21399447.
- ↑ URL: http://www.pathologyoutlines.com/topic/penscrotumpenssqhyper.html. Accessed on: 10 November 2012.
- ↑ URL: http://www.the-dermatologist.com/content/treating-rare-fungal-infections-coccidioidomycosis. Accessed on: 10 November 2012.