Basal crypt dysplasia
Basal crypt dysplasia, abbreviated BCD or CD, is a dysplastic change that involves the crypt bases but not the surface.[1]
It may be referred to as crypt dysplasia.
General
- Molecular changes in the crypt base can be identified in the surface cells.[1]
Microscopic
Features:
- Definite "dysplastic changes" in the crypt base:
- Hyperchromasia - important.
- Nuclear enlargement.
- Nuclear crowding (pseudostratification).
- Non-dysplastic (normal) surface epithelium.[1]