Small round cell tumours

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Revision as of 13:16, 28 September 2010 by Michael (talk | contribs) (clarify)
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Small round cell tumours (SRCT), also small round blue cell tumours (SRBCT), are a group of tumours that have a similar histologic appearance.

It is a group of tumours that is seen more often in childhood than adulthood.

DDx:[1]

  • Neuroblastoma.
  • Wilm's tumour.
  • Alveolar rhabdomyosarcoma.
  • Ewing sarcoma/PNET - this entity is dealt with in the bone article.
  • Lymphoma - large cell lymphomas, e.g. diffuse large B cell lymphoma, anaplastic large cell lymphoma.
  • Retinoblastoma.
  • Hepatoblastoma.
  • Desmoplastic small round cell tumour.

Microscopic

Features:

  • Sheets of cells, very cellular.
  • Small cells ~ 2X RBC diameter.
  • Scant cytoplasm.
  • Coarse chromatin.
  • +/-Nucleolus. (???)
  • +/-Vascular.

See also

References

  1. ↑ URL: http://www.thedoctorsdoctor.com/diseases/small_round_blue_cell_tumor.htm. Accessed on: 2 July 2010.
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