Distal urethral cancers of the penis

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Distal urethral cancers of the penis are very rare cancers.[1]

The main diagnostic considerations are:

IHC

Urothelial carcinoma versus squamous cell carcinoma:[3]

  • GATA-3 +ve in urothelial carcinoma.
  • GATA-3 -ve in squamous cell carcinoma.

See also

References

  1. ↑ 1.0 1.1 Corbishley CM, Rajab RM, Watkin NA (May 2015). "Clinicopathological features of carcinoma of the distal penile urethra". Semin Diagn Pathol 32 (3): 238–44. doi:10.1053/j.semdp.2014.12.015. PMID 25656527.
  2. ↑ Oliva E, Quinn TR, Amin MB, Eble JN, Epstein JI, Srigley JR, Young RH (June 2000). "Primary malignant melanoma of the urethra: a clinicopathologic analysis of 15 cases". Am J Surg Pathol 24 (6): 785–96. doi:10.1097/00000478-200006000-00003. PMID 10843280.
  3. ↑ 3.0 3.1 Chaux A, Han JS, Lee S, Gonzalez-Roibon N, Sharma R, Burnett AL, Cubilla AL, Netto GJ (December 2013). "Immunohistochemical profile of the penile urethra and differential expression of GATA3 in urothelial versus squamous cell carcinomas of the penile urethra". Hum Pathol 44 (12): 2760–7. doi:10.1016/j.humpath.2013.07.023. PMID 24134931.
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