Eye
The eye is rarely seen by pathologists. They go to neuropathologists.
An introduction to neuropathology is in the neuropathology article.
Histology
- The muscles that move the eye have a high nerve:muscle ratio = ~1:4.[1]
- Other muscles in the body ~1:250.
Retinoblastoma
General
- Rare.
- Malignant.
- May be familial.[2]
Microscopic
Features:
- Small round cell tumour.
- Flexner-Wintersteiner rosette - key feature.
- Rosette with empty centre (donut hole).[3]
- +/-Homer-Wright rosette.[4]
- Circular rosette with neuropil at the centre.[3]
Image:
Notes:
- DDx of Flexner-Wintersteiner rosette includes: pineoblastomas, medulloepitheliomas.
Retinal hemorrhage
Image:
See also
References
- ↑ Bilbao. 24 November 2010.
- ↑ Lohmann D (2010). "Retinoblastoma". Adv. Exp. Med. Biol. 685: 220–7. PMID 20687510.
- ↑ 3.0 3.1 Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
- ↑ WH. 14 March 2011.
- ↑ URL: http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/fofrm.html. Accessed on: 6 December 2010.