Talk:Neuropathology tumours
Meningioma
Microscopic
The microscopic section/sections shows a moderately cellular with lesion with prominent whorls, thick-walled blood vessels and focal calcifications.
There are less than 4 mitoses / HPF, where 1 HPF is approximately 0.2376 mm^2. There are no macronucleoli, no sheeting architecture, no hypercellularity, and no spontaneous necrosis. The cells of the lesion do not have a high nuclear-to-cytoplasmic ratio.
Final diagnosis
MENINGIOMA, GRADE 1.
Anaplastic astrocytoma
Microscopic
The microscopic section/sections shows white matter with tumour. The tumour cell nuclei are oblong and have a marked irregular profile and occasionally eosinophilic cytoplasm. Mitoses are rare/common. There is no necrosis and no microvascular proliferation. Immunohistochemistry shows GFAP staining of the perikaryon in cytologically malignant cells. Occasional/Many/All tumour cells stain for p53. The Ki-67 is positive in approximately X% of tumour cells.
Final diagnosis
ANAPLASTIC ASTROCYTOMA, WHO GRADE 3.
Oligodendroglioma
Microscopic
The microscopic section/sections shows regularly distributed cells with round nuclei that are surrounded by clear halos. No mitoses are present. Microvascular proliferation is not seen. The nuclear atypia is mild-to-moderate. There is no nuclear overlapping.
Final diagnosis
OLIGODENDROGLIOMA, WHO GRADE 2.