Eye

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The eye is rarely seen by pathologists. They go to neuropathologists.

An introduction to neuropathology is in the neuropathology article.

Histology

  • The muscles that move the eye have a high nerve:muscle ratio = ~1:4.[1]
    • Other muscles in the body ~1:250.

Conjunctiva:[2]

  • Stratified squamous.
    • May be stratified columnar
  • Goblet cells.

Pterygium

  • AKA surfer eye.

General

  • Pronounced: "tuh-rij-ee-uhm".[3]
  • Conjunctiva lesion that covers part of the sclera.
    • Sclera = white part of the eye.[4]
  • Benign.
  • Assoc. with sun exposure.

Image:

Microscopic

Features:

  • Dilated vessels.
  • Solar elastosis.
    • Dense gray/light brown acellular material.

DDx:

  • Squamous dysplasia.

Image:

Eccrine hidrocystoma

General

  • Benign.
  • Eyelid lesion.

Clinical DDx:[5]

Microsopic

Features:

Retinoblastoma

General

  • Rare.
  • Malignant.
  • May be familial.[6]

Microscopic

Features:

Image:

Notes:

  • DDx of Flexner-Wintersteiner rosette includes: pineoblastomas, medulloepitheliomas.

Retinal hemorrhage

See Traumatic brain injury in infants.

Image:

See also

References

  1. Bilbao. 24 November 2010.
  2. URL: http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm. Accessed on: 20 October 2011.
  3. URL: http://dictionary.reference.com/browse/pterygium. Accessed on: 20 October 2011
  4. URL: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002006/. Accessed on: 20 October 2011.
  5. 5.0 5.1 Adams, SP. (Feb 1999). "Dermacase. Eccrine hydrocystoma.". Can Fam Physician 45: 297, 306. PMC 2328272. PMID 10065300. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2328272/.
  6. Lohmann D (2010). "Retinoblastoma". Adv. Exp. Med. Biol. 685: 220–7. PMID 20687510.
  7. 7.0 7.1 Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
  8. WH. 14 March 2011.
  9. URL: http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/fofrm.html. Accessed on: 6 December 2010.