Giant cell cystitis

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Giant cell cystitis is term used for a benign change of the mesenchymal cells of the urinary bladder lamina propria.

Giant cell cystitis is considered a misnomer as may be seen in an otherwise normal bladder.[1]

General

  • Considered a common benign finding; not a clinical entity.[2]

Microscopic

Features:[3]

  • Scattered atypical mesenchymal cells - mononuclear or multinucleated.
  • +/-Nuclear hyperchromasia and/or lobulation.
  • Absence of apparent mitotic activity.

DDx:

See also

References

  1. Hameed, O.; Humphrey, PA. (Mar 2010). "Pseudoneoplastic mimics of prostate and bladder carcinomas.". Arch Pathol Lab Med 134 (3): 427-43. doi:10.1043/1543-2165-134.3.427. PMID 20196670.
  2. Amin, Mahul B. (2010). Diagnostic Pathology: Genitourinary (1st ed.). Amirsys. pp. 2:6. ISBN 978-1931884280.
  3. Amin, Mahul B.; Eble, John; Grignon, David; Srigley, John. (2013). Urological Pathology (1st ed.). Wolters Kluwer. pp. 305. ISBN 978-0781782814.