Ganglion cyst

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Ganglion cyst is a small benign ditzel.

General

  • Very common.
    • Most common tumour of the hand.[1]
  • Classically on the wrist.[2]
  • May be painful.[3]

Gross

  • Mass at a joint - classically in the hand.

DDx - clinical:

Microscopic

Features:[1][3]

  • Empty space(s); usually multiple.
  • Fibrotic wall.
  • No epithelial lining.†
  • +/-Myxoid change - very common.
    • May have some spindled fibroblasts.


† The entity is really a pseudocyst.[1]

DDx:

Images

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SOFT TISSUE ("GANGLION CYST"), LEFT WRIST, EXCISION:
- GANGLION CYST.

Micro

The sections show fibroadipose tissue with cyst-like spaces surrounded by fibrous tissue. There are no villous projections into the cyst-like spaces. Focal myxoid areas are present with rare bland spindle cells. There is no nuclear atypia and no mitotic activity is appreciated. Dense connective tissue consistent with tendon is present focally.

Alternate

The sections show cyst-like spaces surrounded by fibrous tissue. There are no villous projections into the cyst-like spaces. Focal myxoid areas are present with rare bland spindle cells. There is no nuclear atypia and no mitotic activity is appreciated. Dense connective tissue consistent with tendon is present focally. Benign glands are present.

See also

References

  1. 1.0 1.1 1.2 URL: http://emedicine.medscape.com/article/1253223-overview]. Accessed on: 8 February 2012. Cite error: Invalid <ref> tag; name "emed_gc" defined multiple times with different content
  2. Hasham, S.; Burke, FD. (May 2007). "Diagnosis and treatment of swellings in the hand.". Postgrad Med J 83 (979): 296-300. doi:10.1136/pgmj.2005.043992. PMID 17488856.
  3. 3.0 3.1 3.2 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 322. ISBN 978-0443066542.
  4. Cuono, CB.; Watson, HK. (Jan 1979). "The carpal boss: surgical treatment and etiological considerations.". Plast Reconstr Surg 63 (1): 88-93. PMID 432327.