Eosinophilic fasciitis
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Eosinophilic fasciitis, also diffuse fasciitis with eosinophilia, is a rare skin condition.[1]
General
Clinical:
- Onset typically preceded by strenuous exercise or labour.[2]
- "Orange peel" skin induration.[3]
- Eosinophilia.
Treatment:[4]
- Corticosteroids.
- Methotrexate.
Microscopic
Features:[3]
- Diffuse fasciitis with eosinophilia.
Note:
- Require en bloc biopsies from the skin to the fascia.[2]
References
- ↑ Shulman LE (1975). "Diffuse fasciitis with eosinophilia: a new syndrome?". Trans Assoc Am Physicians 88: 70–86. PMID 1224441.
- ↑ 2.0 2.1 "Eosinophilic fasciitis: From pathophysiology to treatment". Allergol Int 68 (4): 437–439. October 2019. doi:10.1016/j.alit.2019.03.001. PMID 30910631.
- ↑ 3.0 3.1 Mazilu D, Boltașiu Tătaru LA, Mardale DA, Bijă MS, Ismail S, Zanfir V, Negoi F, Balanescu AR (January 2023). "Eosinophilic Fasciitis: Current and Remaining Challenges". Int J Mol Sci 24 (3). doi:10.3390/ijms24031982. PMC 9916848. PMID 36768300. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916848/.
- ↑ Mazori DR, Femia AN, Vleugels RA (November 2017). "Eosinophilic Fasciitis: an Updated Review on Diagnosis and Treatment". Curr Rheumatol Rep 19 (12): 74. doi:10.1007/s11926-017-0700-6. PMID 29101481.