Rheumatoid lung nodule
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| Rheumatoid lung nodule | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | mixed inflammatory infiltrate, +/-giant cells, no micro-organisms |
| LM DDx | necrotic pulmonary nodules in Crohn's disease, infectious pneumonia, amyloidosis of lung |
| Stains | ZN -ve, GMS -ve |
| Site | lung - see medical lung diseases |
|
| |
| Associated Dx | rheumatoid arthritis |
| Clinical history | +/-hx of rheumatoid arthritis |
| Prevalence | uncommon |
| Radiology | upper lung fields, peripheral, round, +/-cavitation |
| Clin. DDx | only lung lesions - esp. malignancy |
Rheumatoid lung nodule, also rheumatoid nodule of the lung and pulmonary rheumatoid nodule, is an uncommon benign lung lesion associated with rheumatoid arthritis.
Rheumatoid lung disease redirects here. Rheumatoid pleuritis is dealt with separately.
General
- Rare.[1]
Common associations:[1]
- Male.
- RF +ve.
- Skin nodules - see rheumatoid nodule.
Gross/radiology
Features:[1]
- Usually upper lung fields, peripheral and round.
- +/-Cavitation (~50% of cases).
Microscopic
Features:[2]
- Mixed inflammatory infiltrate.
- +/-Giant cells.
- No micro-organisms.
Dx:
- Necrotic pulmonary nodule in Crohn's disease.
- Infectious pneumonia.
- Amyloidosis[3] - reported in the context with rheumatoid arthritis.[4]
Images
www:
Stains
- ZN stain -ve for AFB.
- GMS stain -ve for fungal organisms.
- Congo red -ve.
See also
References
- ↑ 1.0 1.1 1.2 Gómez Herrero, H.; Arraiza Sarasa, M.; Rubio Marco, I.; García de Eulate Martín-Moro, I.. "Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases.". Reumatol Clin 8 (4): 212-5. doi:10.1016/j.reuma.2011.09.004. PMID 22265461.
- ↑ 2.0 2.1 2.2 Chhakchhuak, CL.; Khosravi, M.; Lohr, KM. (2013). "Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature.". Case Rep Rheumatol 2013: 621340. doi:10.1155/2013/621340. PMID 23984160.
- ↑ Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H (September 2006). "Nodular pulmonary amyloidosis". Jpn J Thorac Cardiovasc Surg 54 (9): 399–401. doi:10.1007/s11748-006-0015-4. PMID 17037396.
- ↑ Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH (October 2007). "Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis". Clin Rheumatol 26 (10): 1797–8. doi:10.1007/s10067-007-0552-y. PMID 17332981.