BRCA1 interacting protein C-terminal helicase 1
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BRIP1 (BRCA1-interacting protein C-terminal helicase 1; AKA BACH1, FANCJ) is a tumour suppressor gene that interacts with BRCA1 to help repair double-strand DNA breaks. [1] [2] It is a good example of a gene whose mutations cause clinical manifestations that can be dominant or recessive.