Talk:Non-malignant skin disease
Urticaria
Microscopic description
The sections show a mild, superficial dermal perivascular lymphoeosinophilic infiltration. Rare eosinophils are seen in the dermis distant from blood vessels. The epidermis shows normal maturation and is not inflamed. No dysplastic changes are present.
Final diagnosis
A. Skin, posterior left thigh, biopsy - dermal perivascular lymphoeosinophilic infiltration, see comment.
Comment
The sections show a mild, superficial dermal perivascular lymphoeosinophilic infiltration. Rare eosinophils are seen in the dermis distant from blood vessels. The epidermis shows normal maturation and is not inflammed.
Pilomatrixoma
Microscopic description
The sections show a fibrous encapsulated lesion with nests of benign basaloid squamous cells, occasional squamous pearls, multi-nucleated foreign body-type giant cells, and abundant anucleated squamous cells ("ghost cells"). Focal, punctate calcifications are present. Small collections of lymphocytes are present. There is no evidence of dysplasia.
Final diagnosis
Neck mass, left, excision - Pilomatrixoma
Dermatofibroma
Microscopic description
Sections show a well-circumscribed deep dermal, cellular lesion with thick bundles of collagen through-out. The predominant cell type has regular, pale vesicular nuclei without prominent nucleoli and moderate pale cytoplasm. No mitotic activity is present. Histocytes and lymphocytes are present focally. The lesion is incompletely excised. The overlying epidermis and superficial dermis have no pathology.
Final diagnosis
Soft tissue, right anterior calf, excision: - Cellular dermatofibroma.
Dupuytren contracture
Microscopic description
The sections show bland spindle cells in dense collagen. No nuclear atypia is seen.
Final diagnosis
Palmar fascia, left hand, excision: - FIBROMATOSIS CONSISTENT WITH DUPUYTREN'S CONTRACTURE.