Eosinophilic granulomatosis with polyangiitis
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Eosinophilic granulomatosis with polyangiitis, previously known as Churg-Strauss syndrome,[1] is a type of vasculitis.
General
Defining features - memory device GAFE:
- Granulomata.
- Asthma.
- Fever.
- Eosinophilia.
Notes:
- Similar to Granulomatosis with polyangiitis (Wegener's granulomatosis) - classically c-ANCA +ve, and microscopic polyangiitis.[2]
Microscopic
Features:
- Small vessel vasculitis.
- Abundant eosinophils.
- Granulomas.
DDx:
- Eosinophilic vasculitis associated with a connective tissue disease.[3]
Images
CSS - high mag. (WC)
CSS - very high mag. (WC)
See also
References
- ↑ Stone, JR.; Bruneval, P.; Angelini, A.; Bartoloni, G.; Basso, C.; Batoroeva, L.; Buja, LM.; Butany, J. et al. "Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.". Cardiovasc Pathol 24 (5): 267-78. doi:10.1016/j.carpath.2015.05.001. PMID 26051917.
- ↑ URL: http://emedicine.medscape.com/article/334024-overview. Accessed on: 22 January 2011.
- ↑ Chen, KR.; Su, WP.; Pittelkow, MR.; Conn, DL.; George, T.; Leiferman, KM. (Aug 1996). "Eosinophilic vasculitis in connective tissue disease.". J Am Acad Dermatol 35 (2 Pt 1): 173-82. PMID 8708015.