Amnion nodosum
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Amnion nodosum is an uncommon benign placental pathology.
General
- Associated with (long-standing) oligohydramnios.[1]
- Should be separated from squamous metaplasia of amnion.
Gross
Features:[2]
- Yellow nodules ~ 1-5 mm.
- Some think they are white.[3]
DDx:
- Squamous metaplasia of the amnion - large irregular patches, usu. white.
Images
- Amnion nodosum (webpathology.com).
- Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org).[2]
Microscopic
Features:[2]
- Stratified squamous epithelium - non-keratinizing or minimal keratin.
- Amorphous acidophilic (pink) debris.
Note:
- Normal amnion = simple epithelium.
Images
- Amnion nodosum (webpathology.com).
- Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org).[2]
See also
References
- ↑ URL: http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html. Accessed on: 12 January 2011.
- ↑ 2.0 2.1 2.2 2.3 Adeniran, AJ.; Stanek, J. (Dec 2007). "Amnion nodosum revisited: clinicopathologic and placental correlations.". Arch Pathol Lab Med 131 (12): 1829-33. doi:10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2. PMID 18081444.
- ↑ CS. 7 February 2011.