Tubular adenoma of the urinary tract
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| Tubular adenoma of the urinary tract | |
|---|---|
| Diagnosis in short | |
 Tubular adenoma of the urinary tract. H&E stain. | |
|
| |
| LM | glands with pseudostratified hyperchromatic nuclei without maturation to the surface |
| LM DDx | in situ adenocarcinoma of the urinary bladder, adenocarcinoma of the urinary bladder, metastatic adenocarcinoma |
| IHC | CK20 +ve, CDX2 +ve, CK7 -ve, GATA3 -ve |
| Site | urinary tract - urinary bladder, ureter, renal pelvis |
|
| |
| Prevalence | uncommon |
| Prognosis | benign |
Tubular adenoma of the urinary tract is a very rare lesion of the urinary tract that looks like a tubular adenoma of the gastrointestinal tract.[1]
General
- Very rare.
Note:
- Villous adenoma of the urinary tract[2][3] and tubulovillous adenoma of the urinary tract[4] are also reported.
Microscopic
Features:
- Glands with pseudostratified hyperchromatic nuclei without maturation to the surface.
DDx:
- In situ adenocarcinoma of the urinary bladder.
- Adenocarcinoma of the urinary bladder.
- Metastatic adenocarcinoma, e.g. colorectal adenocarcinoma.
Images
TAUT - very low mag. (WC)
TAUT - low mag. (WC)
TAUT - intermed. mag. (WC)
TAUT - high mag. (WC)
IHC
Features:[1]
See also
References
- ↑ 1.0 1.1 Kao, CS.; Epstein, JI. (Sep 2013). "Tubular adenoma of the urinary tract: a newly described entity.". Hum Pathol 44 (9): 1890-4. doi:10.1016/j.humpath.2013.02.017. PMID 23664485.
- ↑ Seibel, JL.; Prasad, S.; Weiss, RE.; Bancila, E.; Epstein, JI. (Feb 2002). "Villous adenoma of the urinary tract: a lesion frequently associated with malignancy.". Hum Pathol 33 (2): 236-41. PMID 11957151.
- ↑ Ratanarapee, S.; Uiprasertkul, M.; Pradniwat, K.; Soontrapa, S. (Nov 2010). "Villous adenoma of the urinary bladder: a case report.". J Med Assoc Thai 93 (11): 1336-9. PMID 21114216.
- ↑ Adegboyega, PA.; Adesokan, A. (Jul 1999). "Tubulovillous adenoma of the urinary bladder.". Mod Pathol 12 (7): 735-8. PMID 10430279.