Pleural invasion
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Pleural invasion is the presence of tumour in the pleura. Pleural invasion is poor prognosticator in lung cancer,[1][2] and important in determining the Tumour stage.
The visceral pleura is the pleura that covers the lung; tumour invasion into it is known as visceral pleural invasion (abbreviated VPI). The parietal pleural covers the chest wall.
Modified Hammar classification
Pleural invasion can be subgrouped as follows:[1]
| Category | Description | Tumour stage (TNM staging) |
|---|---|---|
| PL0 | tumour confined to lung, not through elastic layer | T(any) |
| PL1 | tumour beyond elastic layer of the visercal pleura, not at pleural surface | at least T2 |
| PL2 | tumour at surface of pleura, not in parietal pleura | at least T2 |
| PL3 | tumour within parietal pleura and visceral pleura | at least T3 |
See also
References
- ↑ 1.0 1.1 Travis, WD.; Brambilla, E.; Rami-Porta, R.; Vallières, E.; Tsuboi, M.; Rusch, V.; Goldstraw, P. (Dec 2008). "Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer.". J Thorac Oncol 3 (12): 1384-90. doi:10.1097/JTO.0b013e31818e0d9f. PMID 19057261.
- ↑ Shimizu, K.; Yoshida, J.; Nagai, K.; Nishimura, M.; Ishii, G.; Morishita, Y.; Nishiwaki, Y. (Jul 2005). "Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer.". J Thorac Cardiovasc Surg 130 (1): 160-5. doi:10.1016/j.jtcvs.2004.11.021. PMID 15999057.