Talk:Graft-versus-host disease

Graft-versus-host disease

Colon

Microscopic

A-E. The sections show colonic type mucosa with apoptotic bodies with lymphocyte satellitosis. There are rare scattered neutrophils and eosinophils. There are no exploding crypts and there is no mucosa ulceration. Special stains for CMV, adenovirus and EBV are negative.

Final diagnosis

A-E. Colon, location not specified; colon, splenic flexure; colon, descending; colon, sigmoid; rectum - biopsies (x5) - colonic type mucosa with graft-versus-host disease, grade I.

Esophagus negative

Microscopic

The section shows esophageal mucosa with reactive changes, including elongation of papillae, spongiosis and a mild neutrophilic infiltrate. No apoptotic cells are identified. No ulceration is identified. No vacuolar change of basal cells is identified.

Final diagnosis

Eosphagus, distal, biopsy - Esophageal mucosa with reactive changes. No definitive graft-versus-host-disease identified.