Rheumatoid lung nodule
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Rheumatoid lung nodule | |
---|---|
Diagnosis in short | |
| |
LM | mixed inflammatory infiltrate, +/-giant cells, no micro-organisms |
LM DDx | necrotic pulmonary nodules in Crohn's disease, infectious pneumonia |
Stains | ZN -ve, GMS -ve |
Site | lung - see medical lung diseases |
| |
Associated Dx | rheumatoid arthritis |
Clinical history | +/-hx of rheumatoid arthritis |
Prevalence | uncommon |
Radiology | upper lung fields, peripheral, round, +/-cavitation |
Clin. DDx | only lung lesions - esp. malignancy |
Rheumatoid lung nodule, also rheumatoid nodule of the lung, is an uncommon benign lung lesion associated with rheumatoid arthritis.
Rheumatoid lung disease redirects here. Rheumatoid pleuritis is dealt with separately.
General
- Rare.[1]
Common associations:[1]
- Male.
- RF +ve.
- Skin nodules - see rheumatoid nodule.
Gross/radiology
Features:[1]
- Usually upper lung fields, peripheral and round.
- +/-Cavitation (~50% of cases).
Microscopic
Features:[2]
- Mixed inflammatory infiltrate.
- +/-Giant cells.
- No micro-organisms.
Dx:
- Necrotic pulmonary nodule in Crohn's disease.
- Infectious pneumonia.
Images
www:
Stains
- ZN stain -ve for AFB.
- GMS stain -ve for fungal organisms.
See also
References
- ↑ 1.0 1.1 1.2 Gómez Herrero, H.; Arraiza Sarasa, M.; Rubio Marco, I.; García de Eulate Martín-Moro, I.. "Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases.". Reumatol Clin 8 (4): 212-5. doi:10.1016/j.reuma.2011.09.004. PMID 22265461.
- ↑ 2.0 2.1 2.2 Chhakchhuak, CL.; Khosravi, M.; Lohr, KM. (2013). "Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature.". Case Rep Rheumatol 2013: 621340. doi:10.1155/2013/621340. PMID 23984160.