Insular thyroid carcinoma

From Libre Pathology
Revision as of 14:37, 30 May 2014 by Michael (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Insular thyroid carcinoma, also insular carcinoma, is a rare clinically aggressive form of thyroid carcinoma.[1]

It may be lumped with papillary thyroid carcinoma.

General

Features:[2]

  • Rare - approximately 5% of all thyroid carcinomas.
  • Thought to be a separate tumour from papillary thyroid carcinoma and follicular thyroid carcinoma with a focal insular pattern.
  • Some lump this entity with papillary carcinoma, i.e. consider it a variant of papillary thyroid carcinoma.

Microscopic

Features:[2]

  • Islands of cells - key feature.
  • Scant cytoplasm.
  • Nuclei monomorphic and round.

DDx:[3]

Images

www:

See also

References

  1. Hod R, Bachar G, Sternov Y, Shvero J (2013). "Insular thyroid carcinoma: a retrospective clinicopathologic study". Am J Otolaryngol 34 (4): 292–5. doi:10.1016/j.amjoto.2012.12.009. PMID 23357591.
  2. 2.0 2.1 Rufini V, Salvatori M, Fadda G, et al. (September 2007). "Thyroid carcinomas with a variable insular component: prognostic significance of histopathologic patterns". Cancer 110 (6): 1209–17. doi:10.1002/cncr.22913. PMID 17665497.
  3. Endo. fellow. 17 September 2009.