Eye

The eye is rarely seen by pathologists.

Histology

• The muscles that move the eye have a high nerve:muscle ratio = ~1:4.
  • Other muscles in the body ~1:250.

Retinoblastoma

General

• Rare.
• Malignant.
• May be familial.

Microscopic

Features:

• Small round cell tumour.
• Flexner-Wintersteiner rosette.
  • Rosette with empty centre (donut hole).

Image:

• Retinoblastoma (ouhsc.edu).

Notes:

• DDx of Flexner-Wintersteiner rosette includes: pineoblastomas, medulloepitheliomas.

Retinal hemorrhage

See Traumatic brain injury in infants.

See also

• Hypertension.