Talk:Bone

Aneurysmal bone cyst

Microscopic description

The sections show cartilage, bone and osteoid with variable mineralization surrounded by fibroblasts, hemosiderin-laden macrophages, and multi-nucleated giant-cells with randomly arranged, round nuclei. Hemosiderin-laden macrophages are seen focally. There is no nuclear atypia or mitotic activity. There is no malignant appearing osteoid.

Final diagnosis

Humerous, right proximal, excision - Aneurysmal bone cyst.

Burnt-out chronic osteomyelitis

GREAT TOE, LEFT, AMPUTATION:
- SKIN WITH ULCERATION AND IMPETIGINIZATION.
- ATHEROSCLEROSIS, MODERATE-TO-SEVERE.
- SOFT TISSUE WITH FIBROSIS AND CHRONIC INFLAMMATION.
- BONE AND MILDLY FIBROTIC MARROW SPACE WITH SCATTERED LYMPHOCYTES AND SIDEROPHAGES;
  NO SIGNIFICANT NUMBERS OF PLASMA CELLS OR NEUTROPHILS APPARENT.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.

Osteoporosis

Note:

• There isn't a number for "thin" trabeculae. Anecdotally, I suspect "thin" is 0.15-0.2 mm.
  • Crude guess at normal thickness is ~ 0.4 mm. [1]

1. Klintström, E.; Smedby, O.; Moreno, R.; Brismar, TB. (Nov 2013). "Trabecular bone structure parameters from 3D image processing of clinical multi-slice and cone-beam computed tomography data.". Skeletal Radiol. doi:10.1007/s00256-013-1766-5. PMID 24271010.