Oral pathology

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Oral pathology is a domain of dentistry. In the context of anatomical pathology, it can be lumped with head and neck pathology.

Odontogenic tumours and cysts

Oral neoplasms

Oral fibroma

General

  • Most common oral cavity tumour.[1]
  • Female predominance (female:male = 2:1), usually 30-50 years old.[1]

Microscopic

Features:[4]

  • Fibrous stroma - key feature.
    • "Very pink" at low power.
  • +/-Collagen bundles, may be prominent.
  • Prominent (dilated) vessels.
  • Overlying (squamous) mucosa +/-hyperkeratosis +/-focal ulceration.[1]

Pigmented lesions of the oral cavity

A brief DDx of pigmented lesions:[5]

Smoker's melanosis

General

  • Benign.
  • Seen in ~20% of smokers.[5]
  • Presence of find (smoking) dose-dependent, i.e. longer heavier smokers are more likely to have it.

Gross

  • Typically labial gingvia or buccal mucosa.[5]

Microscopic

Features:

  • Basal melanosis.
  • +/-Melanin incontinence.

Image:

See also

References

  1. 1.0 1.1 1.2 Thompson, Lester D. R. (2006). Head and Neck Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 240. ISBN 978-0443069604.
  2. Segura Saint-Gerons, R.; Ceballos Salobreña, A.; Toro Rojas, M.; Gándara Rey, JM. (Aug 2006). "Oral manifestations of Cowden's disease. Presentation of a clinical case.". Med Oral Patol Oral Cir Bucal 11 (5): E421-4. PMID 16878060.
  3. Oliveira, MA.; Medina, JB.; Xavier, FC.; Magalhães, M.; Ortega, KL. (2010). "Cowden syndrome.". Dermatol Online J 16 (1): 7. PMID 20137749.
  4. 4.0 4.1 Fernandez-Flores, A. (Jul 2010). "Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases.". Am J Dermatopathol 32 (5): 442-7. doi:10.1097/DAD.0b013e3181c47142. PMID 20421776.
  5. 5.0 5.1 5.2 Kauzman, A.; Pavone, M.; Blanas, N.; Bradley, G. (Nov 2004). "Pigmented lesions of the oral cavity: review, differential diagnosis, and case presentations.". J Can Dent Assoc 70 (10): 682-3. PMID 15530266.