Rhabdomyoma

Rhabdomyoma a benign muscle tumour. Often seen in the context of tuberous sclerosis.

General

• May be seen in the context of tuberous sclerosis.

Gross

• Solid, white/tan colour.

Image:

• Cardiac rhabdomyoma (WC/AFIP).

Microscopic

Features - cardiac:

• Spider cells:
  • Large polygonal cells (~10-20x RBC diameter):
    • Abundant cytoplasm filled with glycogen.

DDx:

• Lipoma.
• Fat necrosis.

Images

• 

  Rhabdomyoma - low mag. (WC)

• 

  Rhabdomyoma - intermed. mag. (WC)

• 

  Rhabdomyoma - high mag. (WC)

• 

  Rhabdomyoma - very high mag. (WC)

• 

  Rhabdomyoma - desmin - intermed. mag. (WC)

• 

  Rhabdomyoma - desmin - high mag. (WC)

www

• Rhabdomyoma (brown.edu).
• Rhabdomyoma of the soft palate (webpathology.com).
• Rhabdomyoma (upmc.edu).

See also

• Cardiac tumours.