Serrated polyposis syndrome
Jump to navigation
Jump to search
Hyperplastic polyposis syndrome is an uncommon condition characterized by the presence of (colonic) hyperplastic polyps, may represent several distinct pathologies and is associated with an increased risk of colorectal carcinoma.[1]
WHO definition
One of the following three:[1]
- >=Five hyperplastic polyps proximal to the sigmoid colon with two of the five >=10 mm.
- One hyperplastic polyps proximal to the sigmoid colon, in someone with a first degree relative with the syndrome.
- >30 hyperplastic polyps through-out the colon, i.e. not all can be rectal polyps.
- One source[2] suggests it ought to be >=20 HPs.
References
- ↑ 1.0 1.1 Huang, CS.; Farraye, FA.; Yang, S.; O'Brien, MJ. (Feb 2011). "The clinical significance of serrated polyps.". Am J Gastroenterol 106 (2): 229-40; quiz 241. doi:10.1038/ajg.2010.429. PMID 21045813.
- ↑ URL: http://www.hindawi.com/journals/pri/2011/157073/. Accessed on: 13 December 2011.