Pigmented spindle cell nevus
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Pigmented spindle cell nevus, also pigmented spindle cell nevus of Reed, is an uncommon benign melanocytic lesion.
General
- Uncommon.
- Women in teens & 20s.
Gross
- Location: shoulder, pelvic girdle region.
Microscopic
Features:[1]
- Nests of heavily pigmented spindle cells at dermal-epidermal junction - key feature.
- Nevoid cells in epidermis & dermis - form "basket weave" pattern
- Well-circumscribed lesion.
Notes:
- No epithelioid nevus cells.
DDx:
Images
PSCN - low mag. (WC)
PSCN - intermed. mag. (WC)
PSCN - high mag. (WC)
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SKIN LESION, RIGHT POSTERIOR NECK, EXCISION: - PIGMENTED SPINDLE CELL NEVUS OF REED. -- COMPLETELY EXCISED (CLEARANCE ~ 1 MM).
Micro
The sections show spindled pigmented melanocytes in nests confined to the epidermis. The lesion is symmetrical in its architecture and pigment distribution. There is no pagetoid spread of melanocytes in the epidermis. No significant nuclear atypia is identified. No mitotic activity is appreciated. Melanophages are present in the superficial dermis. The lesion is completely excised in the plane of section.
See also
References
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 500. ISBN 978-0781765275.