Adrenal myelolipoma

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Adrenal myelolipoma is a benign tumour of the adrenal gland.

Adrenal myelolipoma
Diagnosis in short

Myelolipoma. H&E stain.

LM adipose tissue, hematopoietic elements from all three lineages (erythroid, myeloid, megakaryocytic), +/-calcification
Site adrenal gland

Prevalence rare
Prognosis benign
Clin. DDx other adrenal tumours (e.g. adrenal cortical carcinoma)
Treatment excision if large

Myelolipoma redirects here.

General

  • Benign and rare.
  • Typically asymptomatic and hormonally inactive.[1]
    • Symptoms: back or abdominal pain.
  • Diagnosis - usu. by abdominal CT.

Treatment:

  • Watchful waiting if small (<=7 cm) and asymptomatic.[1]

Microscopic

Features:[2]

  • Adipose tissue.
  • Hematopoietic elements from all three lineages:
    1. Erythroid.
    2. Myeloid.
    3. Megakaryocytic.
  • +/-Calcification.[1]

DDx:[3]

Images

www:

See also

References

  1. 1.0 1.1 1.2 Daneshmand, S.; Quek, ML. (2006). "Adrenal myelolipoma: diagnosis and management.". Urol J 3 (2): 71-4. PMID 17590837.
  2. 2.0 2.1 Cha, JS.; Shin, YS.; Kim, MK.; Kim, HJ. (Aug 2011). "Myelolipomas of both adrenal glands.". Korean J Urol 52 (8): 582-5. doi:10.4111/kju.2011.52.8.582. PMC 3162227. PMID 21927708. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162227/.
  3. Lam, KY.; Lo, CY. (Sep 2001). "Adrenal lipomatous tumours: a 30 year clinicopathological experience at a single institution.". J Clin Pathol 54 (9): 707-12. PMID 11533079.