Difference between revisions of "Trisomy 21"

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==Characteristics==
==Characteristics==
Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>
Mnemonic ''CHILD HAS PROBLEM'':<ref>URL: [http://www.valuemd.com/genetics.php http://www.valuemd.com/genetics.php]. Accessed on: 29 May 2011.</ref>
*[[congenital heart disease|'''C'''ongenital heart disease]] / Cataracts.
#[[congenital heart disease|'''C'''ongenital heart disease]] / Cataracts.
*Hypotonia / Hypothyroidism.
#'''H'''ypothyroidism / Hypotonia.
*Incurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.
#'''I'''ncurved 5th digit (clinodactyly)<ref>URL: [http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm]. Accessed on: 29 May 2011.</ref> / Increased gap between 1st and 2nd toe.
*[[Leukemia]] risk x2 / Lung problem.
#[[Leukemia|'''L'''eukemia]] risk x2 / Lung problem.
*Duodenal atresia / Delayed development.
#'''D'''uodenal atresia / Delayed development.
*[[Hirschsprung disease]] / Hearing loss.
#[[Hirschsprung disease|'''H'''irschsprung disease]] / Hearing loss.
*[[Alzheimer disease]] / Alantoaxial instability.
#[[Alzheimer disease|'''A'''lzheimer disease]] / Alantoaxial instability.
*Squint / Short neck.
#'''S'''hort neck / Squint.
*Protruding tongue/ Palmar crease.
#'''P'''almar crease / Protruding tongue.
*Round face / Rolling eye (nystagmus).
#'''R'''ound face / Rolling eye (nystagmus).
*Occiput flat / Oblique eye fissure.
#'''O'''cciput flat / Oblique eye fissure.
*Brushfield spot / Brachycephaly.
#'''B'''rushfield spot / Brachycephaly.
*Low nasal bridge / Language problems.
#'''L'''ow nasal bridge / Language problems.
*Epicanthic fold / Ears folded.
#'''E'''picanthic fold / Ears folded.
*Mental retardation / Myoclonus.
#'''M'''ental retardation / Myoclonus.


==See also==
==See also==

Revision as of 21:01, 29 May 2011

Trisomy 21, also known as Down syndrome, is a common genetic abnormality.

Characteristics

Mnemonic CHILD HAS PROBLEM:[1]

  1. Congenital heart disease / Cataracts.
  2. Hypothyroidism / Hypotonia.
  3. Incurved 5th digit (clinodactyly)[2] / Increased gap between 1st and 2nd toe.
  4. Leukemia risk x2 / Lung problem.
  5. Duodenal atresia / Delayed development.
  6. Hirschsprung disease / Hearing loss.
  7. Alzheimer disease / Alantoaxial instability.
  8. Short neck / Squint.
  9. Palmar crease / Protruding tongue.
  10. Round face / Rolling eye (nystagmus).
  11. Occiput flat / Oblique eye fissure.
  12. Brushfield spot / Brachycephaly.
  13. Low nasal bridge / Language problems.
  14. Epicanthic fold / Ears folded.
  15. Mental retardation / Myoclonus.

See also

References

  1. ↑ URL: http://www.valuemd.com/genetics.php. Accessed on: 29 May 2011.
  2. ↑ URL: http://www.handresearch.com/diagnostics/simian-line-down-syndrome.htm. Accessed on: 29 May 2011.

External links

Retrieved from "https://librepathology.org/w/index.php?title=Trisomy_21&oldid=5697"