Difference between revisions of "Lipofuscin"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
[[Image:Melanosis coli intermed mag.jpg|thumb|right|[[Micrograph]] showing lipofuscin in the colon; this is known as ''[[pseudomelanosis coli]]''. [[H&E stain]].]] | |||
[[Image:Stromal lipofuscinosis of the seminal vesicle - alt -- high mag.jpg |right|thumb|[[Micrograph]] showing stromal lipofuscinosis. [[H&E stain]].]]'''Lipofuscin''' is benign pigment that can be confused for melanin. It is also known as ''age pigment'', as it as associated strongly with aging.<ref name=pmid11976186>{{cite journal |vauthors=Porta EA |title=Pigments in aging: an overview |journal=Ann. N. Y. Acad. Sci. |volume=959 |issue= |pages=57–65 |date=April 2002 |pmid=11976186 |doi=10.1111/j.1749-6632.2002.tb02083.x |url=}}</ref> | [[Image:Stromal lipofuscinosis of the seminal vesicle - alt -- high mag.jpg |right|thumb|[[Micrograph]] showing stromal lipofuscinosis. [[H&E stain]].]]'''Lipofuscin''' is benign pigment that can be confused for melanin. It is also known as ''age pigment'', as it as associated strongly with aging.<ref name=pmid11976186>{{cite journal |vauthors=Porta EA |title=Pigments in aging: an overview |journal=Ann. N. Y. Acad. Sci. |volume=959 |issue= |pages=57–65 |date=April 2002 |pmid=11976186 |doi=10.1111/j.1749-6632.2002.tb02083.x |url=}}</ref> | ||
Revision as of 18:24, 24 May 2020
Lipofuscin is benign pigment that can be confused for melanin. It is also known as age pigment, as it as associated strongly with aging.[1]
Called "melanosis" when it is really lipofuscin
- Bladder lipofuscin pigmentation.[2]
- Pseudomelanosis coli also known as "melanosis coli".[3]
Microscopic
Features:
- Brown pigment.
DDx:
- Melanin.
- Iron.
- Bile.
- Exogenous pigment.
Stains
Features:
- PAS stain +ve.[1]
- Melanin stain -ve.
See also
References
- ↑ 1.0 1.1 "Pigments in aging: an overview". Ann. N. Y. Acad. Sci. 959: 57–65. April 2002. doi:10.1111/j.1749-6632.2002.tb02083.x. PMID 11976186.
- ↑ "Lipofuscin pigmentation (so called "melanosis") of the bladder". Diagn. Cytopathol. 47 (9): 968–971. September 2019. doi:10.1002/dc.24204. PMID 31148387.
- ↑ Freeman HJ (July 2008). ""Melanosis" in the small and large intestine". World J. Gastroenterol. 14 (27): 4296-9. PMID 18666316. http://www.wjgnet.com/1007-9327/14/4296.asp.