Epidermal growth factor receptor inhibitors: Difference between revisions
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'''Epidermal growth factor receptor inhibitors''', abbreviated '''EGFR inhibitors''', is a class of drugs that blocks the EGF receptor. | '''Epidermal growth factor receptor inhibitors''', abbreviated '''EGFR inhibitors''', is a class of drugs that blocks the EGF receptor. | ||
==EGFR== | |||
*EGFR (aka. ErbB1 or HER1) is a membranous receptor expressed in epithelial cells. | |||
*Most of activating mutations in [[NSCLC]] are in Exon 18-21 (kinase domain). | |||
==Drugs== | ==Drugs== | ||