Olfactory neuroblastoma: Difference between revisions
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Jensflorian (talk | contribs) Molecular Data added |
Jensflorian (talk | contribs) →IHC: differences based on mutation status |
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**Small round cells -ve. | **Small round cells -ve. | ||
*[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | *[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | ||
**lower expression of neuroendocrine markers in IDH2 mutant tumors. | |||
Others: | Others: | ||
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*AE1/AE3 usu. -ve (r/o carcinoma). | *AE1/AE3 usu. -ve (r/o carcinoma). | ||
*CAM5.2 usu. -ve -- up to 35% +ve.<ref name=Ref_WMSP41>{{Ref WMSP|41}}</ref> | *CAM5.2 usu. -ve -- up to 35% +ve.<ref name=Ref_WMSP41>{{Ref WMSP|41}}</ref> | ||
**Higher expression of cytokeratins in IDH2 mutant tumors. | |||
==Molecular== | ==Molecular== | ||