Difference between revisions of "Low-grade oncocytic renal tumour"

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*CA9 -ve.
*CA9 -ve.
*CK20 -ve.
*CK20 -ve.
*CD10 -ve.


==See also==
==See also==

Revision as of 14:16, 9 April 2019

Renal oncocytic tumour that is CD117 negative and CK7 positive, also known as low grade oncocytic renal tumour, is unusual renal tumour that does not neatly fit into any WHO renal neoplasia category.

General

  • Very rare.

Microscopic

Features:[1]

  • Oncocytic cytoplasm.
  • Round nuclei.
  • Tubular or solid architecture.
  • Edematous areas with loosly arranged cells.

DDx:

Images

  • LGORT - low mag. (WC)

  • LGORT - intermed. mag. (WC)

  • LGORT - intermed. mag. (WC)

  • LGORT - high mag. (WC)

  • LGORT - high mag. (WC)

  • LGORT - high mag. (WC)

IHC

Features:

  • CD10 -ve/+ve.
  • AMACR -ve/+ve.
  • CA9 -ve.
  • CK20 -ve.
  • CD10 -ve.

See also

References

  1. ↑ Trpkov K, Williamson S, Martinek P, Cheng L, San Miguel Fraile P, Yilmaz A, Hes O, Oncocytic Renal Tumors with CD117 Negative, Cytokeratin 7 Positive Immunoprofile are Different from Eosinophilic Chromophobe Renal Cell Carcinoma (ChrRCC) and Oncocytoma. United States and Canadian Academy of Pathology Annual Meeting 2018.
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