Glioblastoma: Difference between revisions
Jump to navigation
Jump to search
Jensflorian (talk | contribs) →Microscopic: fix ref |
Jensflorian (talk | contribs) →Molecular: pediatric GBM |
||
| Line 162: | Line 162: | ||
**PI3K-pathway genes (7-10%). | **PI3K-pathway genes (7-10%). | ||
*Pediatric glioblastoma | |||
**are morphologically indistinct from adult GBM. | |||
**show frequent H3F3A mutations and PDGFRA mutations (Note: H3F3A K27M mutations are classified as [[Astrocytoma#H3.3_K27M_mutated_glioma_of_the_midline|K27 mutated midline glioma]]). | |||
**Consider Epithelioid GBM, when BRAF V600E mutated. | |||
*Diagnostic/therapeutic relevant markers: | *Diagnostic/therapeutic relevant markers: | ||