Difference between revisions of "Keratinising squamous metaplasia of the urinary bladder"
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'''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal | last1 = Khan | first1 = MS. | last2 = Thornhill | first2 = JA. | last3 = Gaffney | first3 = E. | last4 = Loftus | first4 = B. | last5 = Butler | first5 = MR. | title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. | journal = Eur Urol | volume = 42 | issue = 5 | pages = 469-74 | month = Nov | year = 2002 | doi = | PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal | last1 = Kvist | first1 = E. | last2 = Sjølin | first2 = KE. | last3 = Laursen | first3 = H. | last4 = Orntoft | first4 = TF. | last5 = Sturmer | first5 = MA. | title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. | journal = APMIS | volume = 100 | issue = 7 | pages = 650-4 | month = Jul | year = 1992 | doi = | PMID = 1379440 }}</ref> | '''Keratinising squamous metaplasia of the urinary bladder''' is a rare benign change of the [[urinary bladder]] associated with an increased risk of [[malignancy]];<ref name=pmid12429156>{{Cite journal | last1 = Khan | first1 = MS. | last2 = Thornhill | first2 = JA. | last3 = Gaffney | first3 = E. | last4 = Loftus | first4 = B. | last5 = Butler | first5 = MR. | title = Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience. | journal = Eur Urol | volume = 42 | issue = 5 | pages = 469-74 | month = Nov | year = 2002 | doi = | PMID = 12429156 }}</ref> however, it is not considered a pre-malignant condition.<ref name=pmid1379440>{{Cite journal | last1 = Kvist | first1 = E. | last2 = Sjølin | first2 = KE. | last3 = Laursen | first3 = H. | last4 = Orntoft | first4 = TF. | last5 = Sturmer | first5 = MA. | title = Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients. | journal = APMIS | volume = 100 | issue = 7 | pages = 650-4 | month = Jul | year = 1992 | doi = | PMID = 1379440 }}</ref><ref name=pmid18931537>{{Cite journal | last1 = Ahmad | first1 = I. | last2 = Barnetson | first2 = RJ. | last3 = Krishna | first3 = NS. | title = Keratinizing squamous metaplasia of the bladder: a review. | journal = Urol Int | volume = 81 | issue = 3 | pages = 247-51 | month = | year = 2008 | doi = 10.1159/000151398 | PMID = 18931537 }}</ref> | ||
==General== | ==General== | ||
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*Large age range (13-80 years).<ref name=pmid12429156/> | *Large age range (13-80 years).<ref name=pmid12429156/> | ||
*Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>). | *Predominantly males - almost 4:1 (27 males:7 females in one series<ref name=pmid12429156/>). | ||
Treatment: | |||
*Follow-up is recommended.<ref name=pmid18931537/> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 13:05, 28 April 2016
Keratinising squamous metaplasia of the urinary bladder is a rare benign change of the urinary bladder associated with an increased risk of malignancy;[1] however, it is not considered a pre-malignant condition.[2][3]
General
- Non-keratinizing squamous metaplasia can be considered normal and is relatively common in trigone region of the bladder in women.
- Large age range (13-80 years).[1]
- Predominantly males - almost 4:1 (27 males:7 females in one series[1]).
Treatment:
- Follow-up is recommended.[3]
Microscopic
Features:
- Squamous epithelium with hyperkeratosis or parakeratosis.
DDx:
- Squamous cell carcinoma of the urinary bladder.
- Metastatic squamous cell carcinoma, e.g. squamous cell carcinoma of the uterine cervix.
See also
References
- ↑ 1.0 1.1 1.2 Khan, MS.; Thornhill, JA.; Gaffney, E.; Loftus, B.; Butler, MR. (Nov 2002). "Keratinising squamous metaplasia of the bladder: natural history and rationalization of management based on review of 54 years experience.". Eur Urol 42 (5): 469-74. PMID 12429156.
- ↑ Kvist, E.; Sjølin, KE.; Laursen, H.; Orntoft, TF.; Sturmer, MA. (Jul 1992). "Squamous cell metaplasia of the bladder urothelium. A retrospective study of 36 patients.". APMIS 100 (7): 650-4. PMID 1379440.
- ↑ 3.0 3.1 Ahmad, I.; Barnetson, RJ.; Krishna, NS. (2008). "Keratinizing squamous metaplasia of the bladder: a review.". Urol Int 81 (3): 247-51. doi:10.1159/000151398. PMID 18931537.