Difference between revisions of "Transmembrane mucin 1"
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'''Transmembrane mucin 1''', commonly abbreviated '''MUC1''', is a commonly used [[immunostain]]. | '''Transmembrane mucin 1''', commonly abbreviated '''MUC1''' (or '''MUC-1'''), is a commonly used [[immunostain]]. | ||
It is also known '''epithelial membrane antigen''', abbreviated '''EMA'''.<ref>{{OMIM|158340}}</ref> | It is also known '''epithelial membrane antigen''', abbreviated '''EMA'''.<ref>{{OMIM|158340}}</ref> | ||
A ring or dot-like expression pattern is typical for ependymoma. <ref>{{Cite journal | last1 = Hasselblatt | first1 = M. | last2 = Paulus | first2 = W. | title = Sensitivity and specificity of epithelial membrane antigen staining patterns in ependymomas. | journal = Acta Neuropathol | volume = 106 | issue = 4 | pages = 385-8 | month = Oct | year = 2003 | doi = 10.1007/s00401-003-0752-8 | PMID = 12898159 }}</ref> | A ring or dot-like expression pattern is typical for [[ependymoma]].<ref>{{Cite journal | last1 = Hasselblatt | first1 = M. | last2 = Paulus | first2 = W. | title = Sensitivity and specificity of epithelial membrane antigen staining patterns in ependymomas. | journal = Acta Neuropathol | volume = 106 | issue = 4 | pages = 385-8 | month = Oct | year = 2003 | doi = 10.1007/s00401-003-0752-8 | PMID = 12898159 }}</ref> | ||
===Images=== | |||
<gallery> | <gallery> | ||
File:Miningioma (4) EMA.JPG | EMA staining in a meningioma (WC/KGH) | File:Miningioma (4) EMA.JPG | EMA staining in a [[meningioma]]. (WC/KGH) | ||
File:EMA_dots_ependymoma.jpg | EMA staining in a ependymoma (WC/jensflorian) | File:EMA_dots_ependymoma.jpg | EMA staining in a ependymoma. (WC/jensflorian) | ||
</gallery> | </gallery> | ||
Revision as of 20:45, 18 September 2015
Transmembrane mucin 1, commonly abbreviated MUC1 (or MUC-1), is a commonly used immunostain.
It is also known epithelial membrane antigen, abbreviated EMA.[1]
A ring or dot-like expression pattern is typical for ependymoma.[2]
Images
EMA staining in a meningioma. (WC/KGH)
EMA staining in a ependymoma. (WC/jensflorian)
_EMA.JPG)
See also
References
- ↑ Online 'Mendelian Inheritance in Man' (OMIM) 158340
- ↑ Hasselblatt, M.; Paulus, W. (Oct 2003). "Sensitivity and specificity of epithelial membrane antigen staining patterns in ependymomas.". Acta Neuropathol 106 (4): 385-8. doi:10.1007/s00401-003-0752-8. PMID 12898159.