Difference between revisions of "Follicular thyroid carcinoma"

From Libre Pathology
Jump to navigation Jump to search
(→‎Images: more)
Line 37: Line 37:


===Images===
===Images===
<gallery>
Image:Metastatic_follicular_thyroid_carcinoma_-_Case_264_(8559837390).jpg | Metastatic FTC. (WC/Yale Rosen)
Image:Metastatic_follicular_thyroid_carcinoma_-_Case_264_(8558730243).jpg | Metastatic FTC. (WC/Yale Rosen)
</gallery>
www:
www:
*[http://path.upmc.edu/cases/case653.html Follicular thyroid carcinoma - several images (upmc.edu)].
*[http://path.upmc.edu/cases/case653.html Follicular thyroid carcinoma - several images (upmc.edu)].

Revision as of 03:58, 4 March 2015

Follicular thyroid carcinoma, abbreviated FTC, is an uncommon malignancy of the thyroid gland. It is also known as follicular carcinoma.

General

  • Usually spread by the hematologic route.
    • PTC usually spreads via lymphatics.

Clinical

Medical school memory device 4 Fs:

  • FNA NOT diagnosable.
  • Far away mets (sometimes).
  • Female predominant.
  • Favourable prognosis.

Gross

  • Encapuslated lesion +/-evidence of invasion through the capsule.

Images

Microscopic

Features:

  • Defined by either:
    1. Invasion through the capsule:
      • Should be all the way through.[1]
        • 1/2 does not count.
        • Fibrous reaction does not count.
        • "Above the contour" does not count.
    2. Vascular invasion (all of the following):
      1. In a small vein (not a capillary), that is outside of the tumour mass.
      2. Tumour adherent to the side of the vessel.
      3. Tumour must be re-endothelialized.

Notes:

  • Impossible to differentiate from follicular adenoma on FNA (no cytologic differences).
  • Described as "over-diagnosed" ... misdiagnoses: PTC follicular variant, follicular adenoma, multinodular goitre with a thick capsule.

Images

www:

See also

References

  1. SR. 17 January 2011.