Difference between revisions of "Dysembryoplastic neuroepithelial tumour"

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'''Dysembryoplastic neuroepithelial tumour''', abbreviated '''DNT''', is a rare [[neuropathology tumour]] that is associated with [[epilepsy]].
'''Dysembryoplastic neuroepithelial tumour''', abbreviated '''DNET''',<ref name=pmid25311417>{{Cite journal  | last1 = Alexander | first1 = H. | last2 = Tannenburg | first2 = A. | last3 = Walker | first3 = DG. | last4 = Coyne | first4 = T. | title = Progressive dysembryoplastic neuroepithelial tumour. | journal = J Clin Neurosci | volume = 22 | issue = 1 | pages = 221-4 | month = Jan | year = 2015 | doi = 10.1016/j.jocn.2014.07.022 | PMID = 25311417 }}</ref> is a rare [[neuropathology tumour]] that is associated with [[epilepsy]].


==General==
==General==

Revision as of 22:14, 16 February 2015

Dysembryoplastic neuroepithelial tumour, abbreviated DNET,[1] is a rare neuropathology tumour that is associated with epilepsy.

General

  • Common tumour cause of drug resistant epilepsy.[2]
  • Paediatric population.

Gross/radiology

  • Temporal lobe.
  • Variable architecture:[3] cystic, solitary nodular, multinodular.

Microscopic

Features:[3]

  • Cells similar to oligodendrocytes:
    • Large central nuclei with indentations.
    • Multiple small nucleoli (common).
    • Clear cytoplasm.

DDx:

Images

www:

See also

References

  1. Alexander, H.; Tannenburg, A.; Walker, DG.; Coyne, T. (Jan 2015). "Progressive dysembryoplastic neuroepithelial tumour.". J Clin Neurosci 22 (1): 221-4. doi:10.1016/j.jocn.2014.07.022. PMID 25311417.
  2. Cataltepe, O.; Turanli, G.; Yalnizoglu, D.; Topçu, M.; Akalan, N. (Apr 2005). "Surgical management of temporal lobe tumor-related epilepsy in children.". J Neurosurg 102 (3 Suppl): 280-7. doi:10.3171/ped.2005.102.3.0280. PMID 15881751.
  3. 3.0 3.1 3.2 O'Brien, DF.; Farrell, M.; Delanty, N.; Traunecker, H.; Perrin, R.; Smyth, MD.; Park, TS. (Dec 2007). "The Children's Cancer and Leukaemia Group guidelines for the diagnosis and management of dysembryoplastic neuroepithelial tumours.". Br J Neurosurg 21 (6): 539-49. doi:10.1080/02688690701594817. PMID 18071981.