Difference between revisions of "Tuberous sclerosis-associated renal cell carcinoma"
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'''Tuberous sclerosis-associated renal cell carcinoma''', abbreviated '''TSARCC''', is a [[ | '''Tuberous sclerosis-associated renal cell carcinoma''', abbreviated '''TSARCC''', is a [[kidney tumour]] that is associated with the syndrome [[tuberous sclerosis]].<ref name=pmid25093518>{{Cite journal | last1 = Guo | first1 = J. | last2 = Tretiakova | first2 = MS. | last3 = Troxell | first3 = ML. | last4 = Osunkoya | first4 = AO. | last5 = Fadare | first5 = O. | last6 = Sangoi | first6 = AR. | last7 = Shen | first7 = SS. | last8 = Lopez-Beltran | first8 = A. | last9 = Mehra | first9 = R. | title = Tuberous Sclerosis-associated Renal Cell Carcinoma: A Clinicopathologic Study of 57 Separate Carcinomas in 18 Patients. | journal = Am J Surg Pathol | volume = 38 | issue = 11 | pages = 1457-67 | month = Nov | year = 2014 | doi = 10.1097/PAS.0000000000000248 | PMID = 25093518 }}</ref> | ||
==General== | ==General== |
Revision as of 03:36, 14 November 2014
Tuberous sclerosis-associated renal cell carcinoma, abbreviated TSARCC, is a kidney tumour that is associated with the syndrome tuberous sclerosis.[1]
General
- Not in the WHO classification of renal neoplasia.
- Afflicts individuals at a younger age than sporadic renal cell carcinoma.[2]
Microscopic
Features - one of three morphologies:[1]
- Renal angiomyoadenomatous tumour-like.
- Chromophobe renal cell carcinoma-like.
- Macrocystic architecture with cells with granular eosinophilic cytoplasm.
DDx:
- Renal angiomyoadenomatous tumour.
- Chromophobe renal cell carcinoma.
- Hereditary leiomyomatosis renal cell carcinoma syndrome-associated renal cell carcinoma.
See also
References
- ↑ 1.0 1.1 Guo, J.; Tretiakova, MS.; Troxell, ML.; Osunkoya, AO.; Fadare, O.; Sangoi, AR.; Shen, SS.; Lopez-Beltran, A. et al. (Nov 2014). "Tuberous Sclerosis-associated Renal Cell Carcinoma: A Clinicopathologic Study of 57 Separate Carcinomas in 18 Patients.". Am J Surg Pathol 38 (11): 1457-67. doi:10.1097/PAS.0000000000000248. PMID 25093518.
- ↑ Bjornsson, J.; Short, MP.; Kwiatkowski, DJ.; Henske, EP. (Oct 1996). "Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features.". Am J Pathol 149 (4): 1201-8. PMID 8863669.