Difference between revisions of "Thyroid-like follicular carcinoma of the kidney"
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'''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''', is a recently described rare [[kidney tumour]]. | '''Thyroid-like follicular carcinoma of the kidney''', also '''thyroid-like follicular renal cell carcinoma''' (abbreviated '''TLF-RCC'''), is a recently described rare [[kidney tumour]]. | ||
It is considered an emerging entity by the ''[[Vancouver classification|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | last3 = Eble | first3 = JN. | last4 = Egevad | first4 = L. | last5 = Epstein | first5 = JI. | last6 = Grignon | first6 = D. | last7 = Hes | first7 = O. | last8 = Moch | first8 = H. | last9 = Montironi | first9 = R. | title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. | journal = Am J Surg Pathol | volume = 37 | issue = 10 | pages = 1469-89 | month = Oct | year = 2013 | doi = 10.1097/PAS.0b013e318299f2d1 | PMID = 24025519 }}</ref> | It is considered an emerging entity by the ''[[Vancouver classification|Vancouver modification of the 2004 WHO classification of renal neoplasia]]''.<ref name=pmid24025519>{{Cite journal | last1 = Srigley | first1 = JR. | last2 = Delahunt | first2 = B. | last3 = Eble | first3 = JN. | last4 = Egevad | first4 = L. | last5 = Epstein | first5 = JI. | last6 = Grignon | first6 = D. | last7 = Hes | first7 = O. | last8 = Moch | first8 = H. | last9 = Montironi | first9 = R. | title = The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia. | journal = Am J Surg Pathol | volume = 37 | issue = 10 | pages = 1469-89 | month = Oct | year = 2013 | doi = 10.1097/PAS.0b013e318299f2d1 | PMID = 24025519 }}</ref> |
Revision as of 05:00, 27 October 2014
Thyroid-like follicular carcinoma of the kidney, also thyroid-like follicular renal cell carcinoma (abbreviated TLF-RCC), is a recently described rare kidney tumour.
It is considered an emerging entity by the Vancouver modification of the 2004 WHO classification of renal neoplasia.[1]
General
- Extremely rare - less than 15 cases reported in the literature.[1]
- Large age range (29-83 years old).
Gross
- Solid, brown and well circumscribed.
Microscopic
Features:[1]
- Thyroid follicule-like structures - both microfollicular and/or microfollicular. **Contain dense-appearing eosinophilic material.
- Encapuslated.
- Nuclei round and regular with prominent nucleoli (ISUP nucleolar grade 2 or 3).
DDx:
- Metastatic carcinoma.
Images
IHC
Features:[1]
- TTF-1 -ve.
- Thyroglobulin -ve.
- CK7 +ve/-ve.
- PAX8 +ve/-ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Srigley, JR.; Delahunt, B.; Eble, JN.; Egevad, L.; Epstein, JI.; Grignon, D.; Hes, O.; Moch, H. et al. (Oct 2013). "The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.". Am J Surg Pathol 37 (10): 1469-89. doi:10.1097/PAS.0b013e318299f2d1. PMID 24025519.
- ↑ Ghaouti, M.; Roquet, L.; Baron, M.; Pfister, C.; Sabourin, JC. (2014). "Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature.". Diagn Pathol 9 (1): 186. doi:10.1186/s13000-014-0186-8. PMID 25293503.