Difference between revisions of "Thyroid-like follicular carcinoma of the kidney"
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**[[Follicular thyroid carcinoma]]. | **[[Follicular thyroid carcinoma]]. | ||
**[[Papillary thyroid carcinoma follicular variant]]. | **[[Papillary thyroid carcinoma follicular variant]]. | ||
===Images=== | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190304/figure/Fig3/ TLF-RCC (nih.gov)].<ref name=pmid25293503>{{Cite journal | last1 = Ghaouti | first1 = M. | last2 = Roquet | first2 = L. | last3 = Baron | first3 = M. | last4 = Pfister | first4 = C. | last5 = Sabourin | first5 = JC. | title = Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature. | journal = Diagn Pathol | volume = 9 | issue = 1 | pages = 186 | month = | year = 2014 | doi = 10.1186/s13000-014-0186-8 | PMID = 25293503 }}</ref> | |||
==IHC== | ==IHC== |
Revision as of 04:59, 27 October 2014
Thyroid-like follicular carcinoma of the kidney, also thyroid-like follicular renal cell carcinoma, is a recently described rare kidney tumour.
It is considered an emerging entity by the Vancouver modification of the 2004 WHO classification of renal neoplasia.[1]
General
- Extremely rare - less than 15 cases reported in the literature.[1]
- Large age range (29-83 years old).
Gross
- Solid, brown and well circumscribed.
Microscopic
Features:[1]
- Thyroid follicule-like structures - both microfollicular and/or microfollicular. **Contain dense-appearing eosinophilic material.
- Encapuslated.
- Nuclei round and regular with prominent nucleoli (ISUP nucleolar grade 2 or 3).
DDx:
- Metastatic carcinoma.
Images
IHC
Features:[1]
- TTF-1 -ve.
- Thyroglobulin -ve.
- CK7 +ve/-ve.
- PAX8 +ve/-ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Srigley, JR.; Delahunt, B.; Eble, JN.; Egevad, L.; Epstein, JI.; Grignon, D.; Hes, O.; Moch, H. et al. (Oct 2013). "The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia.". Am J Surg Pathol 37 (10): 1469-89. doi:10.1097/PAS.0b013e318299f2d1. PMID 24025519.
- ↑ Ghaouti, M.; Roquet, L.; Baron, M.; Pfister, C.; Sabourin, JC. (2014). "Thyroid-like follicular carcinoma of the kidney: a case report and review of the literature.". Diagn Pathol 9 (1): 186. doi:10.1186/s13000-014-0186-8. PMID 25293503.